South Africa Vaccinations & Health Rules for South Africans 2026

Last checked July 2026 — always confirm with official sources before travelling.

For South African citizens travelling within South Africa or returning to South Africa, there is no yellow fever risk in the country and yellow fever vaccination is not routinely recommended for travel within South Africa. However, South Africa requires travellers aged 1 year and older to carry a valid International Certificate of Vaccination or Prophylaxis (ICVP) when arriving from a country with yellow fever transmission risk, or after transiting for more than 12 hours through an airport in such a country.

Before a safari, South African travellers should check routine immunisations, discuss hepatitis A and typhoid based on their itinerary, obtain personalised malaria advice where relevant, and carry health and medication documentation. Requirements can change, so confirm the route with the South African Department of Health, an accredited travel clinic and the airline before departure.

Quick answer: required versus recommended vaccines

Vaccine or document	Is it required?	What South African travellers should know
Yellow fever certificate	Only for certain arrival or transit routes	Required for travellers aged 1 and over arriving from a yellow-fever-risk country or transiting for more than 12 hours through its airport. The vaccine must be administered at least 10 days before arrival, and the certificate must be recorded on a valid ICVP.
Routine vaccines	Not described as a South Africa entry requirement in the supplied official guidance	CDC advises travellers to be up to date with routine vaccines before every trip.
Hepatitis A	Not listed as a universal entry requirement	CDC recommends hepatitis A vaccination for unvaccinated travellers aged 1 year and older going to South Africa; infants aged 6–11 months should also be vaccinated, although that dose does not count toward the routine two-dose series.
Typhoid	Not a universal entry requirement	Recommended for most travellers, particularly people staying with friends or relatives or visiting smaller cities and rural areas.
Rabies and hepatitis B	Not a universal entry requirement in the supplied guidance	Ask a clinician whether they fit your activities, accommodation, duration and personal health circumstances. DIRCO advises South Africans to make timely enquiries about destination health risks and to consult a doctor when they have existing health challenges.

For planning logistics alongside health, SafariFind's South Africa safari guide for 2026 can help you identify the regions and activities that should be discussed with a travel-health professional.

Yellow fever certificate rules for South Africa

When is a yellow fever certificate required?

South Africa requires a valid ICVP for travellers aged 1 year and older who arrive from a country with risk of yellow fever virus transmission. The same requirement applies when a traveller transits for more than 12 hours through the airport of such a country. The rule is based on the traveller's recent route, not on whether the traveller is a South African citizen.

There is no yellow fever transmission risk in South Africa, and the CDC does not recommend yellow fever vaccination solely for travel within the country. The certificate requirement exists to reduce the risk of importing the virus from a risk area.

How long before travel must the vaccine be given?

The yellow fever vaccine must be administered at least 10 days before arrival in South Africa for the certificate to meet the stated requirement. South Africa's government guidance says the vaccine should be approved by the World Health Organization and administered at an approved yellow fever vaccination centre.

A properly documented single yellow fever dose on an ICVP is valid for the traveller's lifetime under the CDC Yellow Book guidance. Carry the original ICVP with your passport and travel documents rather than relying only on a photograph or a clinic receipt.

What if a traveller cannot be vaccinated?

A medical waiver signed by a licensed healthcare professional is generally accepted for entry when a traveller cannot receive the vaccine for medical reasons. The CDC states that travellers with a medical waiver are generally allowed entry, while South African government guidance provides for medical exemptions.

Do not assume that a waiver eliminates every border-health step. Confirm the precise documentation with an approved vaccination centre, the relevant South African authority and the airline before travel. A traveller who does not meet the certificate requirement may be refused entry or quarantined for up to six days, according to the CDC Yellow Book.

Recommended vaccinations and timing

Routine vaccines

Start by checking whether routine vaccinations are current. CDC guidance says travellers should be up to date with routine vaccines before every trip and identifies COVID-19 vaccination as part of current travel-health advice for eligible travellers.

Your clinician may review protection against diseases included in the South African routine immunisation programme and your personal vaccination history. The exact recommendation depends on age, pregnancy status, medical conditions, previous doses and the activities planned, so this article does not replace an individual consultation.

Hepatitis A

Hepatitis A vaccination is recommended by the CDC for unvaccinated travellers aged 1 year and older travelling to South Africa. The CDC also says infants aged 6–11 months should be vaccinated; this early dose does not count toward the routine two-dose series.

Discuss timing with a travel clinic as soon as you know your departure date. Bring your vaccination record so the clinician can determine whether you are already protected or need additional doses.

Typhoid

Typhoid vaccination is recommended for most travellers, especially those staying with friends or relatives or visiting smaller cities and rural areas. It is not presented in the supplied official guidance as a universal entry requirement for South Africa.

Rabies, hepatitis B and other itinerary-based vaccines

Rabies and hepatitis B decisions should be individualised. Tell the clinician whether you will handle animals, spend extended periods in rural areas, work in healthcare, stay for a long period, travel with children or have medical conditions that affect vaccine choices. The CDC's South Africa guidance includes rabies among the travel-health topics to review, while DIRCO advises South Africans to seek advice about health risks and prescribed immunisations or medication before travelling.

Book a travel-health consultation early enough to complete any recommended schedule and to discuss side effects, contraindications and travel insurance. If your safari includes another country, do not apply South Africa's advice automatically. For example, travellers comparing a Tanzania versus South Africa safari should check Tanzania's separate health and entry requirements.

Malaria: risk areas, prophylaxis and prevention

Malaria planning is itinerary-specific. A safari in South Africa may involve different exposure considerations from an urban stay, a coastal holiday or travel that continues into another country. The research available for this article does not provide a current province-by-province malaria map, a universal list of medicines or a single prophylaxis schedule; do not self-prescribe based on a generic safari checklist.

Before travelling, show a clinician your complete route, dates, accommodation, planned game drives, walking activities and onward destinations. Ask whether malaria prevention medicine is appropriate, which option suits your health profile and when it should be started, taken and stopped. This is particularly important for pregnancy, childhood travel, allergies, chronic conditions and medicine interactions.

Medication is only one part of prevention. Ask the clinic about avoiding mosquito bites and follow its advice on clothing, accommodation and personal protection. If you develop a fever during or after a safari, tell the healthcare professional about your recent travel and possible mosquito exposure; seek medical care promptly rather than assuming the illness is a routine cold.

South African travellers planning a wildlife trip can compare safari packages on SafariFind, but the package description should not be treated as medical advice. Confirm whether the itinerary enters areas requiring a malaria discussion before booking transport and activities.

Health documents and travel insurance

Carry a passport, your original ICVP if your route triggers the yellow fever rule, vaccination records, prescriptions and a written list of medicines and allergies. The ICVP is the document used to record yellow fever vaccination for international travel.

Keep paper copies separately from your originals and store secure digital copies where they can be accessed offline. Ask your doctor whether a letter should explain any prescription medicines, medical devices or special supplies. The research does not establish a universal South African insurance requirement or a standard insurance fee, so confirm policy terms directly with the insurer.

Travel insurance should be checked for medical treatment, evacuation, pre-existing conditions, safari activities and cancellations. DIRCO advises South African citizens to research health risks before travel and to consult a doctor when they have a history of health challenges.

If you travel internationally after South Africa, review the next country's requirements before leaving. South African citizens abroad can use a South African embassy, high commission or consulate-general, email ROSAhelp@dirco.gov.za or register through the DIRCO Travel Smart App, according to the South African government's current registration guidance.

Medication rules and what to pack

Pack enough regular medication for the planned journey and keep it in its labelled packaging. Put essential medicine in your hand luggage rather than relying only on checked baggage. Ask your prescribing clinician or pharmacist about storage, time-zone changes, replacement prescriptions and whether a medical letter is appropriate.

Do not buy or carry an antimalarial, antibiotic or other prescription medicine solely because it appears on an online safari packing list. The correct medicine depends on the traveller and itinerary, and the research supplied does not support a single medicine or dosage for all South Africa trips.

A practical health kit can include prescribed medicines, a copy of prescriptions, vaccination records, sunscreen, insect-bite protection recommended by your clinician, basic wound-care supplies and any personal medical devices. These are packing suggestions, not South African border requirements. Check airline rules separately for liquids, needles and medical equipment.

Travellers with allergies or ongoing conditions should tell companions and safari staff what to do in an emergency. Families should carry children's health records and ask a clinician about age-appropriate vaccines and medicines before departure.

Health facilities and emergencies in South Africa

Choose accommodation and activities with access to an appropriate healthcare plan, particularly when travelling to remote reserves. Before departure, ask your operator how medical assistance, transport and evacuation are handled in the specific reserve and region; arrangements differ by itinerary.

In a medical emergency, seek immediate local medical assistance and contact your insurer's emergency assistance service. For non-urgent concerns, use a qualified doctor, clinic or hospital and provide your travel route, vaccination history, current medicines and symptoms.

Safari activities can involve distance from urban healthcare, animal encounters, heat, dehydration and insect exposure. Follow the operator's safety briefing, disclose relevant medical conditions and do not approach wildlife outside the rules of the reserve. If your trip focuses on conservation or wildlife, the South Africa wildlife conservation organisations guide provides useful background, but it is not a substitute for a medical risk assessment.

Health requirements change. Recheck South African government guidance, CDC destination advice, your airline's documentation rules and your travel clinic's recommendations shortly before departure. If your itinerary includes a yellow-fever-risk country, verify the transit duration as well as the departure country, because a connection longer than 12 hours can trigger the certificate requirement.

Frequently Asked Questions

Do South African citizens need a yellow fever vaccine for South Africa?

Not for travel within South Africa or a route that does not involve a yellow-fever-risk country. South Africa requires a valid ICVP for travellers aged 1 and over arriving from a yellow-fever-risk country or transiting for more than 12 hours through its airport.

How long before entering South Africa should I get the yellow fever vaccine?

Get it at least 10 days before arrival. South Africa's government guidance says the vaccine should be administered at an approved yellow fever vaccination centre, and the CDC requires documentation on a valid ICVP.

How long is a South Africa yellow fever certificate valid?

A properly documented single yellow fever dose is valid for the traveller's lifetime under CDC Yellow Book guidance. Keep the vaccination recorded on a valid ICVP.

What happens if I arrive in South Africa without a yellow fever certificate?

You may be refused entry or quarantined for up to six days if the route triggers the certificate rule. A medical waiver signed by a licensed healthcare professional is generally accepted for travellers who cannot be vaccinated.

What vaccinations are recommended for a South Africa safari?

Check routine vaccines first, then discuss hepatitis A, typhoid and itinerary-specific vaccines such as rabies or hepatitis B with a travel-health professional. CDC recommends hepatitis A for unvaccinated travellers aged 1 and older and typhoid for most travellers, especially those visiting rural areas or smaller cities.

Is hepatitis A vaccination recommended for South Africa?

Yes, CDC recommends it for unvaccinated travellers aged 1 year and older travelling to South Africa. CDC also recommends vaccination for infants aged 6–11 months, although that dose does not count toward the routine two-dose series.

Is typhoid vaccination required for South Africa?

No universal typhoid entry requirement is identified in the supplied official guidance. CDC recommends typhoid vaccination for most travellers, especially people staying with friends or relatives or visiting smaller cities and rural areas.

Do I need malaria tablets for a South Africa safari?

That depends on your exact route, dates, activities and health profile, so ask a travel-health professional rather than self-prescribing. The available research does not support one malaria medicine or schedule for every South Africa safari.

What health documents should South African travellers carry?

Carry your vaccination record, prescriptions, medicine list and, when your route triggers the rule, the original yellow fever ICVP. The ICVP is the document used to record yellow fever vaccination for international travel.

Where can South African citizens get travel-health advice?

Consult a doctor or travel-health clinic and check South African Department of Health guidance before departure. DIRCO also advises South African travellers to make timely enquiries about health risks and prescribed immunisations or medication.