Vaccinations & Health Rules for Ethiopia: US Citizens 2026

Quick Answer: Vaccine & Health Requirements for US Citizens to Ethiopia

Yellow fever: Not required for direct travel from the United States, but recommended for all travelers ≥9 months old visiting most of Ethiopia (except Afar and Somali regions). Required if you transit for more than 12 hours through a yellow fever risk country en route.

Malaria prophylaxis: Recommended for all areas below 2,000 meters year-round (except Addis Ababa). Risk is highest May–August.

Hepatitis A: Recommended for all travelers.

Routine vaccinations: Ensure you are up to date before travel.

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Yellow Fever: Entry Requirements & Recommendations

Do You Need a Yellow Fever Certificate to Enter Ethiopia?

If you are traveling directly from the United States to Ethiopia, a yellow fever vaccination certificate is not required by Ethiopian authorities. However, the CDC recommends vaccination for your own protection.

If your itinerary includes a stopover or transit of more than 12 hours in a country with yellow fever risk (such as Brazil, Peru, or many sub-Saharan African nations), you will need proof of yellow fever vaccination to enter Ethiopia, even if you're just transiting through an airport.

Countries with yellow fever risk include Angola, Benin, Burkina Faso, Cameroon, Central African Republic, Chad, Democratic Republic of Congo, Côte d'Ivoire, Gabon, Ghana, Guinea, Guinea-Bissau, Kenya, Liberia, Mali, Nigeria, Sudan, Uganda, and others in Africa and South America.

Yellow Fever Vaccination Recommendations

The CDC recommends yellow fever vaccination for all travelers ≥9 months old visiting Ethiopia, with the following exception:

• Generally not recommended: Vaccination is generally not recommended if your travel is limited to the Afar or Somali regions, where yellow fever transmission risk is low. However, if you plan any travel outside these regions or have prolonged exposure to mosquitoes, vaccination should be considered.

Yellow fever is transmitted by Aedes aegypti mosquitoes, which bite during the day and especially around dawn and dusk. The virus can cause fever, jaundice, bleeding, organ failure, and in severe cases, death.

Yellow Fever Vaccination Timing

Receive your yellow fever vaccine at least 10 days before departure. The vaccine provides immunity for life in most cases; a single dose is sufficient. The vaccine becomes effective approximately 10 days after administration, so plan ahead.

If you are allergic to vaccine components, speak with your travel health provider about alternative protection, such as immune globulin (effective for up to 2 months depending on dosage).

Yellow Fever Certificate Validity

The International Certificate of Vaccination or Prophylaxis (ICVP) documenting yellow fever vaccination is valid for life. Keep this certificate with your passport; it may be required when entering other countries after Ethiopia.

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Recommended Vaccinations for Ethiopia Travel

Hepatitis A

Recommended for all travelers of all ages to Ethiopia. Hepatitis A is spread through contaminated food and water.

Vaccination schedule: Two doses given 6–12 months apart. You can receive the first dose at least 2 weeks before travel; some protection begins after the first dose, with full protection after the second dose.

Routine Vaccinations

Ensure you are up to date on all routine vaccinations recommended by the CDC before traveling to any destination. These include:

• Measles, mumps, and rubella (MMR)
• Diphtheria, tetanus, and pertussis (Tdap)
• Polio (IPV)
• Varicella (chickenpox)
• Influenza (annual flu vaccine)
• Pneumococcal disease
• Meningococcal disease

Confirm your routine vaccination status with your healthcare provider at least 4–6 weeks before travel.

Other Vaccines to Discuss with Your Travel Health Provider

Depending on your itinerary, personal risk factors, and length of stay, your healthcare provider may recommend:

• Typhoid: Recommended for travelers, especially those visiting rural areas or eating at local restaurants.
• Hepatitis B: Recommended if there is potential for exposure through sexual contact, medical procedures, or occupational exposure.
• Rabies: Consider if you will be in remote areas or have close animal contact.
• Meningococcal disease: Particularly relevant during meningitis season (dry months, December–March).
• Polio booster: If you have not received a booster in 10 years and plan to visit areas with poliovirus risk.

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Malaria: Risk Areas, Prophylaxis & Prevention

Where Is Malaria Risk in Ethiopia?

Malaria risk exists throughout Ethiopia year-round in areas below 2,000 meters (6,560 feet) elevation. There is no malaria risk in Addis Ababa, the capital city, which sits at approximately 2,400 meters.

The parasite types in Ethiopia are approximately 60% Plasmodium falciparum and 40% Plasmodium vivax. Chloroquine-resistant P. vivax has been reported.

Risk is highest during the rainy season, typically May–August.

Malaria Prophylaxis (Antimalarial Medications)

If you are traveling to areas below 2,000 meters, consult a travel medicine specialist or your healthcare provider at least 4–6 weeks before departure to determine the right antimalarial medication for you. The choice depends on your itinerary, length of stay, pregnancy status, and other health factors.

Common options recommended by the CDC for Ethiopia include atovaquone-proguanil (Malarone), doxycycline, and mefloquine. Your provider will advise which is most appropriate.

Timing: Start antimalarial medication before you arrive in the malaria zone (typically 1–2 days before, depending on the drug), continue during your stay, and continue for 4 weeks after you leave the malaria zone.

Mosquito Bite Prevention

Antimalarial medication is not 100% effective; mosquito bite prevention is equally important:

• Use insect repellent containing 20–30% DEET on exposed skin.
• Wear long sleeves and long pants, especially during dawn and dusk when Anopheles mosquitoes (which transmit malaria) are most active.
• Sleep under an insecticide-treated bed net if your accommodation is not air-conditioned or well-screened.
• Stay in air-conditioned or well-screened rooms when possible.

If you develop fever, chills, or flu-like symptoms during or after your trip, seek medical care immediately and inform your healthcare provider that you traveled to a malaria-endemic area.

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Other Health Risks & Preventive Measures

Food and Water Safety

Travelers' diarrhea is common in Ethiopia. Reduce risk by:

• Drinking only bottled, boiled, or purified water (avoid tap water and ice).
• Eating only thoroughly cooked foods served hot.
• Avoiding raw or undercooked meat, seafood, and unpasteurized dairy.
• Washing hands frequently with soap and clean water.

Consider carrying loperamide (Imodium) and an antibiotic (such as azithromycin or ciprofloxacin) for self-treatment of moderate to severe diarrhea; consult your healthcare provider about which antibiotic is appropriate for you.

Tuberculosis (TB)

TB is present in Ethiopia. If you have close contact with TB patients or prolonged exposure, discuss TB testing (tuberculin skin test or interferon-gamma release assay) with your healthcare provider before and after travel.

Other Insect-Borne Diseases

Dengue fever, chikungunya, Zika, and other arthropod-borne diseases may pose a risk in parts of Ethiopia. Mosquito bite prevention measures (DEET repellent, protective clothing, bed nets) reduce transmission risk.

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Health Documents & Travel Insurance

What Health Documents Should You Carry?

• International Certificate of Vaccination or Prophylaxis (ICVP): Carry the yellow card documenting your yellow fever vaccination. This may be required when entering other countries after Ethiopia.
• Vaccination records: Keep records of all vaccinations (hepatitis A, routine vaccines, etc.) in case you need to provide proof to healthcare providers in Ethiopia or upon return.
• Prescription medications: Carry medications in original, labeled containers. Bring a letter from your healthcare provider describing any chronic conditions and medications.
• Travel insurance: Obtain comprehensive travel insurance that covers evacuation and medical care abroad. Ethiopia's healthcare system is limited, especially outside Addis Ababa.

Travel Insurance Recommendation

Ensure your travel insurance covers medical evacuation, emergency hospitalization, and repatriation. This is critical, as serious medical conditions may require evacuation to Kenya or Europe for advanced care.

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Medication Rules & What to Pack

Bringing Medications into Ethiopia

Pack all medications in original, labeled containers. Carry a letter from your healthcare provider describing your medical conditions and the names, doses, and purposes of all medications. Quantities should be reasonable for personal use.

Ethiopia has restrictions on certain medications, particularly controlled substances. If you require opioids, sedatives, or other controlled medications, consult the Ethiopian embassy or your healthcare provider well before travel.

What to Pack: Health & Hygiene Kit

• Antimalarial medication (prescribed)
• Antibiotic for diarrhea (prescribed)
• Loperamide (Imodium) for diarrhea
• Pain reliever (acetaminophen or ibuprofen)
• Antihistamine for allergies
• Decongestant
• Anti-nausea medication
• Insect repellent (20–30% DEET)
• Sunscreen (SPF 30+)
• First-aid supplies (bandages, antiseptic, tweezers for tick removal)
• Any personal prescription medications
• Malaria rapid diagnostic test kit (optional; ask your travel health provider)

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Healthcare Facilities & Emergencies in Ethiopia

Medical Care in Ethiopia

Healthcare facilities in Ethiopia are limited, particularly outside Addis Ababa. The U.S. Embassy maintains a list of doctors and hospitals in Addis Ababa but does not endorse any specific provider. Medical facilities may lack supplies, advanced diagnostics, and specialist services available in the United States.

In Addis Ababa, some private clinics and hospitals offer reasonable care for minor illnesses and injuries. However, serious conditions typically require medical evacuation to Kenya, the Middle East, or Europe.

Emergency Contacts

U.S. Embassy Addis Ababa: +251 11 517 40 00 (during business hours) or +251 911 50 66 55 (after hours emergency line).

Register with the Smart Traveler Enrollment Program (STEP) at step.state.gov before travel so the embassy can contact you in case of emergency.

Air Quality & Environmental Health

Air pollution can be significant in Addis Ababa and other urban areas, particularly during the dry season. Travelers with respiratory conditions (asthma, COPD) should carry appropriate medications and consider a mask during high-pollution days.

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Pre-Travel Planning Checklist

• 4–6 weeks before travel: Schedule an appointment with a travel medicine specialist or your healthcare provider to discuss vaccinations, malaria prophylaxis, and health risks.
• Confirm yellow fever vaccination timing: Receive the vaccine at least 10 days before departure.
• Start hepatitis A series: First dose should be given at least 2 weeks before travel.
• Obtain antimalarial prescription: Start medication on the correct schedule (typically 1–2 days before entering the malaria zone).
• Update routine vaccinations: Ensure all routine vaccines are current.
• Arrange travel insurance: Confirm coverage for medical evacuation and emergency care.
• Register with STEP: Enroll with the U.S. State Department's Smart Traveler Enrollment Program.
• Obtain medical records: Request a letter from your healthcare provider listing medications and conditions.
• Pack health kit: Assemble medications, repellent, sunscreen, and first-aid supplies.

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When planning your Ethiopia adventure, you can also explore Ethiopia visa requirements for American citizens and compare safari lodges and packages on SafariFind to ensure your trip is fully organized.

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Frequently Asked Questions

Do American citizens need a yellow fever vaccine to enter Ethiopia?

Not if traveling directly from the United States. However, the CDC recommends vaccination for your protection. A certificate is required only if you have transited for more than 12 hours through a yellow fever risk country.

What vaccinations are recommended for US citizens traveling to Ethiopia?

Yellow fever (except for Afar and Somali regions), hepatitis A, routine vaccines (MMR, Tdap, polio, varicella, flu), and possibly typhoid, hepatitis B, and meningococcal. Your travel health provider will tailor recommendations to your itinerary.

Is malaria a risk in Addis Ababa?

No. Addis Ababa sits at 2,400 meters elevation, above the malaria transmission zone (areas below 2,000 meters). However, if you travel to lower-altitude regions, malaria prophylaxis is recommended.

How long before travel should I get vaccinated?

Schedule a travel medicine appointment 4–6 weeks before departure. Yellow fever vaccine should be given at least 10 days before travel; hepatitis A first dose at least 2 weeks before.

What antimalarial medication should I take to Ethiopia?

The choice depends on your itinerary, pregnancy status, and medical history. Common options include atovaquone-proguanil, doxycycline, and mefloquine. Consult a travel health provider for a personalized recommendation.

Can I bring my prescription medications into Ethiopia?

Yes, in original, labeled containers with a letter from your healthcare provider. Quantities should be reasonable for personal use. Avoid bringing controlled substances without explicit permission from Ethiopian authorities.

What should I do if I develop fever during my trip?

Seek medical care immediately. Inform healthcare providers that you are in a malaria-endemic area. Bring your antimalarial medication history and vaccination records.

Is travel insurance necessary for Ethiopia?

Strongly recommended. Ensure coverage includes medical evacuation and emergency hospitalization, as serious medical conditions may require transport outside Ethiopia.

Do I need to be vaccinated against yellow fever if I'm only visiting Afar and Somali regions?

Vaccination is generally not recommended for travel limited to these regions, as yellow fever transmission risk is low. However, discuss with your healthcare provider if you have extended mosquito exposure.

How long is a yellow fever vaccination certificate valid?

A single dose provides lifelong immunity in most cases. The ICVP (yellow card) is valid for life and should be kept with your passport.

What food and water precautions should I take?

Drink only bottled, boiled, or purified water. Eat only thoroughly cooked foods served hot. Avoid raw or undercooked meat, seafood, and unpasteurized dairy. Wash hands frequently.

Where can I find medical care in Ethiopia?

The U.S. Embassy maintains a list of doctors and hospitals in Addis Ababa. For serious conditions, medical evacuation to Kenya or Europe may be necessary. Arrange travel insurance that covers evacuation.

Frequently Asked Questions

Do American citizens need a yellow fever vaccine to enter Ethiopia?

Not if traveling directly from the United States. However, the CDC recommends vaccination for your protection, as yellow fever is present in most of Ethiopia. A vaccination certificate is required only if you have transited for more than 12 hours through a yellow fever risk country (such as Brazil, Peru, or most sub-Saharan African nations).

What vaccinations are recommended for US citizens traveling to Ethiopia?

Yellow fever (except for Afar and Somali regions), hepatitis A, and routine vaccines (MMR, Tdap, polio, varicella, influenza) are recommended for all travelers. Depending on your itinerary and health profile, your travel health provider may also recommend typhoid, hepatitis B, rabies, meningococcal, or a polio booster.

Is malaria a risk in Addis Ababa?

No. Addis Ababa, the capital, sits at approximately 2,400 meters elevation, above the malaria transmission zone. However, if you travel to areas below 2,000 meters, malaria prophylaxis is recommended year-round, with highest risk May–August.

How long before my trip should I get vaccinated for Ethiopia?

Schedule a travel medicine appointment at least 4–6 weeks before departure. Yellow fever vaccine should be administered at least 10 days before travel; hepatitis A first dose at least 2 weeks before. This allows time for immunity to develop and for any side effects to resolve.

What antimalarial medication should I take to Ethiopia?

The choice depends on your itinerary, length of stay, pregnancy status, and medical history. Common CDC-recommended options include atovaquone-proguanil (Malarone), doxycycline, and mefloquine. Consult a travel health provider for a personalized recommendation 4–6 weeks before travel.

Can I bring my prescription medications into Ethiopia?

Yes, in original, labeled containers with a letter from your healthcare provider describing your medical conditions and medications. Quantities should be reasonable for personal use. Avoid bringing controlled substances (opioids, sedatives) without explicit permission from Ethiopian authorities.

What should I do if I develop fever or malaria symptoms during my trip?

Seek medical care immediately. Inform healthcare providers that you are in a malaria-endemic area, and bring your antimalarial medication history and vaccination records. If fever develops, it may indicate malaria, dengue, or another serious infection requiring prompt diagnosis and treatment.

Is travel insurance necessary for a trip to Ethiopia?

Strongly recommended. Ensure coverage includes medical evacuation and emergency hospitalization abroad, as serious medical conditions may require transport outside Ethiopia to Kenya or Europe for advanced care.

How long is a yellow fever vaccination certificate valid?

A single dose of yellow fever vaccine provides lifelong immunity in most cases. Your International Certificate of Vaccination or Prophylaxis (ICVP, or yellow card) is valid for life and should be kept with your passport, as it may be required when entering other countries after Ethiopia.

What food and water safety precautions should I take in Ethiopia?

Drink only bottled, boiled, or purified water; avoid tap water and ice. Eat only thoroughly cooked foods served hot; avoid raw or undercooked meat, seafood, and unpasteurized dairy. Wash hands frequently with soap and clean water to prevent travelers' diarrhea and other foodborne illness.

Where can I find medical care if I become ill in Ethiopia?

The U.S. Embassy maintains a list of doctors and hospitals in Addis Ababa but does not endorse specific providers. Healthcare outside the capital is limited. For serious conditions, medical evacuation to Kenya, the Middle East, or Europe may be necessary—ensure your travel insurance covers evacuation.

Do I need a yellow fever vaccine if I'm only visiting Afar and Somali regions?

Vaccination is generally not recommended for travel limited to these regions, as yellow fever transmission risk is low. However, if you plan to travel outside these regions or have extended mosquito exposure, vaccination should be considered. Discuss your specific itinerary with a travel health provider.